Central Nervous System

1

INI CET MDS MAY 2023 [General Medicine- Central Nervous System]

Question

Disease which is caused due to protein misfolding

OPTION 1

Creutzfeldt-Jakob disease (CJD) is a rare, rapidly worsening disorder of central nervous system that causes unique changes in brain tissue and affects muscle coordination thinking, and memory.
What causes Creutzfeldt-Jakob disease?
CJD appears to be caused by an abnormal infectious protein called a prion. These prions accumulate at high levels in the brain and cause irreversible damage to nerve cells. While the abnormal prions are technically infectious, they're very different from viruses and bacteria.